Location: South San Francisco, CA / Flexible

TRexBio is a discovery stage biotechnology company leveraging cutting edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for inflammatory diseases. Our powerful ‘deep biology’ discovery engine maps human tissue T_reg behavior to disease processes, allowing us to identify and characterize novel targets for therapeutic intervention. Leveraging this platform, we are building a broad portfolio of novel therapies that modulate the immune system to restore human tissue immune homeostasis.

Our Culture:

At TRexBio, you will have the opportunity to work with amazingly smart humans who strive to make the world a better place. In addition to our team-centric culture, we believe that your individual creativity will help us to be our best. Our staff happy hours, organized by our Culture Club, bring us all together in creative and social activities. Our colleagues admire and respect one another.  We celebrate our wins, update company news and acknowledge each other’s achievement weekly and monthly at all company meetings that celebrate our work and our people.

Position Summary:

We are seeking a talented and highly-motivated scientist to join our Translational Biology Research group. Our team is dedicated to the exploration of target biology and drug mechanisms. This position will direct in vivo immunology and pharmacology activities, including exploratory biomarkers in murine models. Prior drug development experience in immunomodulatory biologics is required. The candidate is expected to have deep knowledge of autoimmune-related disease biology and a thorough understanding of relevant mouse models.

Key Responsibilities include but are not limited to:

• Design and management of mouse model studies at CROs
• Direction of a team of scientists to perform pharmacodynamic and biomarker analyses
• Preparation of relevant sections for regulatory findings

Required Qualifications:

• PhD in immunology (or closely-related field)
• 8+ years of postdoctoral industry experience, including at least 4 years in immunology-related protein therapeutics
• Expertise in in vivo models of autoimmune disease biology
• Detail-oriented and analytical with excellent problem-solving skills
• Proven ability to collaborate in a team-oriented, matrixed environment
• Good planning and organizational skills to meet deadlines

Preferred Qualifications:

• Experience directing research activities during the IND-enabling phase of biologic drug development
• Management experience

TRexBio offers a very competitive benefits including medical, dental, vision, short/long term disability, life insurance as well as 401(k) match, bonus and paid time leave.

TRexBio is proud to be an AA/EEO employer and all qualified candidates will receive consideration without regard to characteristics protected by applicable local, state, or federal law, such as race, color, sex, age, religion, national origin, physical or mental disability, pregnancy, marital status, veteran or military status, genetic information, or sexual orientation.