Senior Scientist/Principal Scientist, Translational Biology (Tissue Immunology)

Location: South San Francisco, CA / Flexible

TRexBio is a discovery stage biotechnology company leveraging cutting edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for inflammatory diseases. Our powerful ‘deep biology’ discovery engine maps human tissue Treg behavior to disease processes, allowing us to identify and characterize novel targets for therapeutic intervention. Leveraging this platform, we are building a broad portfolio of novel therapies that modulate the immune system to restore human tissue immune homeostasis.

Our Culture:

At TRexBio, you will have the opportunity to work with amazingly smart humans who strive to make the world a better place. In addition to our team-centric culture, we believe that your individual creativity will help us to be our best. Our staff happy hours, organized by our Culture Club, bring us all together in creative and social activities. Our colleagues admire and respect one another.  We celebrate our wins, update company news and acknowledge each other’s achievement weekly and monthly at all company meetings that celebrate our work and our people.

Position Summary:

We are seeking a talented and highly-motivated scientist to join our Translational Biology Research group. Our team is dedicated to the exploration of target biology and drug mechanisms. This position is responsible for ex vivo tissue immunology activities, including human 3D and explant tissue assay platforms. The position required bench research as well as group management.  Prior industry experience in immunomodulatory biologics is desired. The candidate is expected to have deep knowledge of immune-related disease biology and up-to-date expertise in immunology research methodology and technology.

Key Responsibilities include but are not limited to:

  • Development and expansion of human tissue model capabilities

Required Qualifications:

  • PhD in immunology (or closely-related field)
  • 6+ years of postdoctoral experience
  • Expertise in ex vivo tissue-based models
  • Detail-oriented and analytical with excellent problem-solving skills
  • Proven ability to collaborate in a team-oriented, matrixed environment
  • Good planning and organizational skills to meet deadlines

Preferred Qualifications:

  • 4+ years of industry research experience in the area of autoimmunity or immuno-oncology
  • Management experience

TRexBio offers a very competitive benefits including medical, dental, vision, short/long term disability, life insurance as well as 401(k) match, bonus and paid time leave.

TRexBio is proud to be an AA/EEO employer and all qualified candidates will receive consideration without regard to characteristics protected by applicable local, state, or federal law, such as race, color, sex, age, religion, national origin, physical or mental disability, pregnancy, marital status, veteran or military status, genetic information, or sexual orientation.

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