Decoding Human T issue Biology to C reate Revolutionary T herapeutics
TRexBio is creating purpose-built biologics aimed at restoring immune balance in autoimmune and inflammatory diseases. By addressing the disease where it presents, in the tissue, our goal is to quiet the inflammatory process and restore tissue homeostasis.
Unlocking Precise, Actionable Therapeutic Insights
TRexBio’s Deep Biology Platform decodes regulatory T cell (Treg) behavior in human tissues, mapping the key drivers of immune dysregulation and uncovering targets and insights for therapeutic intervention and product development.
We start with a robust collection of human tissue across health and disease. Leveraging a suite of modern sequencing and computational tools, paired with disease-relevant human assay systems, we generate translatable insights to create novel tissue Treg-focused therapeutics for immune-mediated diseases.
Unlocking precise, actionable therapeutic insights
TRexBio’s Deep Biology Platform decodes regulatory T cells (Treg) behavior in human tissues, mapping the key drivers of immune dysregulation and uncovering targets and insights for therapeutic intervention and product development.
We start with a robust collection of human tissue across health and disease. Leveraging a suite of modern sequencing and computational tools, paired with disease-relevant human assay systems, we generate translatable insights to create novel tissue Treg-focused therapeutics for immune-mediated diseases.
The Future of Treg Therapeutics
Our lead candidate, TRB-061, is a TNFR2 agonist designed to selectively augment suppressive Tregs in tissue. It is in clinical development for atopic dermatitis and has potential across a range of inflammatory diseases.
In addition to TRB-061, we are advancing a robust pipeline of wholly owned programs to address significant unmet needs in dermatology, gastroenterology, and beyond.
We’re Built for Breakthroughs
TRexBio brings together broad expertise across immunology, functional genomics, and clinical development. Our team is united by a shared goal: to bring durable, disease-modifying therapies to patients living with immune-mediated conditions.
We are a team that is better together, welcoming differences in backgrounds, opinions, and experiences.